Do I need to set-up my artwork file differently for different colors of Tote Bags?

No, the setup is the same regardless of which bag color you choose. The one thing to watch is the background of your artwork.

• Keep the background transparent wherever you want the bag color to show through
• Anything you fill with color in the file will print as ink, covering the bag underneath
• Design the same way for Natural, Blue, or Red bags
• Preview your art against the bag color to confirm contrast reads well

A transparent background lets the fabric color become part of the design instead of being hidden by a printed block.